Anti-Recombinant-F9/Factor IX antibody [RM1H38] (STJA0023329)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Coagulation Factor Ix for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1H38 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | F9 |
| Gene ID | 2158 |
| Uniprot ID | FA9_HUMAN |
Additional Info
| Post Translational Modifications | Activated by factor XIa, which excises the activation peptide. The propeptide can also be removed by snake venom protease. Activated by coagulation factor VIIa-tissue factor (F7-F3) complex in calcium-dependent manner. The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. |
| Function | Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa. |
| Protein Name | Coagulation Factor IxChristmas FactorPlasma Thromboplastin ComponentPtc Cleaved Into - Coagulation Factor Ixa Light Chain - Coagulation Factor Ixa Heavy Chain |
| Database Links | Reactome: R-HSA-140834Reactome: R-HSA-140837Reactome: R-HSA-159740Reactome: R-HSA-159763Reactome: R-HSA-159782Reactome: R-HSA-9629569Reactome: R-HSA-9672383Reactome: R-HSA-9672396Reactome: R-HSA-9673202Reactome: R-HSA-9673218Reactome: R-HSA-9673221Reactome: R-HSA-9673240 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Coagulation Factor Ix antibodyAnti-Christmas Factor antibodyAnti-Plasma Thromboplastin Component antibodyAnti-Ptc Cleaved Into - Coagulation Factor Ixa Light Chain - Coagulation Factor Ixa Heavy Chain antibodyAnti-F9 antibody |
Information sourced from Uniprot.org