| Function | Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. |
| Protein Name | Coagulation Factor Xiii A ChainCoagulation Factor XiiiaProtein-Glutamine Gamma-Glutamyltransferase A ChainTransglutaminase A Chain |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-140875Reactome: R-HSA-6785807 |
| Cellular Localisation | CytoplasmSecretedSecreted Into The Blood PlasmaCytoplasmic In Most TissuesBut Also Secreted In The Blood Plasma |
| Alternative Antibody Names | Anti-Coagulation Factor Xiii A Chain antibodyAnti-Coagulation Factor Xiiia antibodyAnti-Protein-Glutamine Gamma-Glutamyltransferase A Chain antibodyAnti-Transglutaminase A Chain antibodyAnti-F13A1 antibodyAnti-F13A antibody |
Information sourced from Uniprot.org
