Anti-Recombinant-EPN1 antibody [RM2L29] (STJA0025993)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Epsin-1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2L29 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | EPN1 |
| Gene ID | 29924 |
| Uniprot ID | EPN1_HUMAN |
Additional Info
| Function | Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis. |
| Protein Name | Epsin-1Eh Domain-Binding Mitotic PhosphoproteinEps-15-Interacting Protein 1 |
| Database Links | Reactome: R-HSA-182971Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinNucleusMembraneClathrin-Coated PitAssociated With The Cytoplasmic Membrane At Sites Where Clathrin-Coated Pits Are FormingColocalizes With Clathrin And Ap-2 In A Punctate Pattern On The Plasma MembraneDetected In Presynaptic Nerve Terminals And In Golgi StacksMay Shuttle To The Nucleus When Associated With Zbtb16/Znf145 |
| Alternative Antibody Names | Anti-Epsin-1 antibodyAnti-Eh Domain-Binding Mitotic Phosphoprotein antibodyAnti-Eps-15-Interacting Protein 1 antibodyAnti-EPN1 antibody |
Information sourced from Uniprot.org