Anti-Recombinant-EFEMP1/Fibulin-3 antibody [RM2D37] (STJA0025308)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Egf-Containing Fibulin-Like Extracellular Matrix Protein 1 for use in IHC, IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2D37 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | EFEMP1 |
| Gene ID | 2202 |
| Uniprot ID | FBLN3_HUMAN |
Additional Info
| Function | Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth. |
| Protein Name | Egf-Containing Fibulin-Like Extracellular Matrix Protein 1Extracellular Protein S1-5Fibrillin-Like ProteinFibulin-3Fibl-3 |
| Database Links | Reactome: R-HSA-2129379 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixLocalizes To The Lamina Propria Underneath The Olfactory Epithelium |
| Alternative Antibody Names | Anti-Egf-Containing Fibulin-Like Extracellular Matrix Protein 1 antibodyAnti-Extracellular Protein S1-5 antibodyAnti-Fibrillin-Like Protein antibodyAnti-Fibulin-3 antibodyAnti-Fibl-3 antibodyAnti-EFEMP1 antibodyAnti-FBLN3 antibodyAnti-FBNL antibody |
Information sourced from Uniprot.org