Anti-Recombinant-DSC3 antibody [RM2F56] (STJA0025525)

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STJA0025525
£300.50 - £457.50
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Short Description :Rabbit monoclonal anti-Recombinant-Desmocollin-3 for use in FC, IF and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC/IF/WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :RM2F56
Isotype:IgG
Conjugation:Unconjugated
Purification:Protein A/G purified from cell culture supernatant
Dilution Range:FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000
Formulation:0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol:DSC3
Gene ID:1825
Uniprot ID:DSC3_HUMAN
Function A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Required for cell-cell adhesion in the epidermis, as a result required for the maintenance of the dermal cohesion and the dermal barrier function. Required for cell-cell adhesion of epithelial cell layers surrounding the telogen hair club, as a result plays an important role in telogen hair shaft anchorage. Essential for successful completion of embryo compaction and embryo development.
Protein Name Desmocollin-3
Cadherin Family Member 3
Desmocollin-4
Ht-Cp
Database Links Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Desmosome
Cytoplasm
Expressed In The Cytoplasm And At The Cell Membrane Of Oocytes
Alternative Antibody Names Anti-Desmocollin-3 antibody
Anti-Cadherin Family Member 3 antibody
Anti-Desmocollin-4 antibody
Anti-Ht-Cp antibody
Anti-DSC3 antibody
Anti-CDHF3 antibody
Anti-DSC4 antibody

Information sourced from Uniprot.org