Anti-Recombinant-DNAJB6 antibody [RM1F10] (STJA0023103)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Dnaj Homolog Subfamily B Member 6 for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1F10 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:50-1:100 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | DNAJB6 |
| Gene ID | 10049 |
| Uniprot ID | DNJB6_HUMAN |
Additional Info
| Function | Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Also reduces cellular toxicity and caspase-3 activity. Isoform B: Isoform B but not isoform A inhibits huntingtin aggregation. |
| Protein Name | Dnaj Homolog Subfamily B Member 6Hhdj1Heat Shock Protein J2Hsj-2MrjMsj-1 |
| Database Links | Reactome: R-HSA-3371453 |
| Cellular Localisation | CytoplasmPerinuclear RegionNucleusMyofibrilSarcomereZ Line |
| Alternative Antibody Names | Anti-Dnaj Homolog Subfamily B Member 6 antibodyAnti-Hhdj1 antibodyAnti-Heat Shock Protein J2 antibodyAnti-Hsj-2 antibodyAnti-Mrj antibodyAnti-Msj-1 antibodyAnti-DNAJB6 antibodyAnti-HSJ2 antibodyAnti-MRJ antibodyAnti-MSJ1 antibody |
Information sourced from Uniprot.org