Anti-Recombinant-DNAJA1 antibody [RM1U27] (STJA0024407)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Dnaj Homolog Subfamily A Member 1 for use in FC, IP and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1U27 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | FCM: 1:20-1:100 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | DNAJA1 |
| Gene ID | 3301 |
| Uniprot ID | DNJA1_HUMAN |
Additional Info
| Function | Co-chaperone for HSPA8/Hsc70. Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as a co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis. Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV. |
| Protein Name | Dnaj Homolog Subfamily A Member 1Dnaj Protein Homolog 2HsdjHeat Shock 40 Kda Protein 4Heat Shock Protein J2Hsj-2Human Dnaj Protein 2Hdj-2 |
| Database Links | Reactome: R-HSA-3371497Reactome: R-HSA-9841251 |
| Cellular Localisation | MembraneLipid-AnchorCytoplasmMicrosomeNucleusPerinuclear RegionMitochondrionPrimarily Associated With MicrosomesA Minor Proportion Is Associated With MitochondriaPrimarily CytoplasmicA Minor Proportion Is Associated With Nuclei |
| Alternative Antibody Names | Anti-Dnaj Homolog Subfamily A Member 1 antibodyAnti-Dnaj Protein Homolog 2 antibodyAnti-Hsdj antibodyAnti-Heat Shock 40 Kda Protein 4 antibodyAnti-Heat Shock Protein J2 antibodyAnti-Hsj-2 antibodyAnti-Human Dnaj Protein 2 antibodyAnti-Hdj-2 antibodyAnti-DNAJA1 antibodyAnti-DNAJ2 antibodyAnti-HDJ2 antibodyAnti-HSJ2 antibodyAnti-HSPF4 antibody |
Information sourced from Uniprot.org