Anti-Recombinant-DGKA antibody [RM1S47] (STJA0024229)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Diacylglycerol Kinase Alpha for use in IHC, IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1S47 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:50-1:100 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | DGKA |
| Gene ID | 1606 |
| Uniprot ID | DGKA_HUMAN |
Additional Info
| Function | Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids (Probable). Can also phosphorylate 1-alkyl-2-acylglycerol in vitro as efficiently as diacylglycerol provided it contains an arachidonoyl group. Also involved in the production of alkyl-lysophosphatidic acid, another bioactive lipid, through the phosphorylation of 1-alkyl-2-acetyl glycerol. |
| Protein Name | Diacylglycerol Kinase AlphaDag Kinase Alpha80 Kda Diacylglycerol KinaseDiglyceride Kinase AlphaDgk-Alpha |
| Database Links | Reactome: R-HSA-114508 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Diacylglycerol Kinase Alpha antibodyAnti-Dag Kinase Alpha antibodyAnti-80 Kda Diacylglycerol Kinase antibodyAnti-Diglyceride Kinase Alpha antibodyAnti-Dgk-Alpha antibodyAnti-DGKA antibodyAnti-DAGK antibodyAnti-DAGK1 antibody |
Information sourced from Uniprot.org