Anti-Recombinant-DCTN3 antibody [RM1F82] (STJA0023175)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Dynactin Subunit 3 for use in IF, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1F82 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | DCTN3 |
| Gene ID | 11258 |
| Uniprot ID | DCTN3_HUMAN |
Additional Info
| Function | Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules. Together with dynein may be involved in spindle assembly and cytokinesis. |
| Protein Name | Dynactin Subunit 3Dynactin Complex Subunit 22 Kda SubunitP22 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-2565942Reactome: R-HSA-3371497Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-6807878Reactome: R-HSA-6811436Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeChromosomeCentromereKinetochoreSpindleCleavage FurrowMidbodyLocalizes To Punctate Cytoplasmic Structures And To The Centrosome During InterphaseAnd To Kinetochores And To Spindle Poles Throughout MitosisColocalizes With Dynein To The Cleavage Furrow And To Midbody Of Dividing Cells |
| Alternative Antibody Names | Anti-Dynactin Subunit 3 antibodyAnti-Dynactin Complex Subunit 22 Kda Subunit antibodyAnti-P22 antibodyAnti-DCTN3 antibodyAnti-DCTN22 antibody |
Information sourced from Uniprot.org