Anti-Recombinant-CDC37 antibody [RM2H04] (STJA0025671)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJA0025671
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General Information

Short DescriptionRabbit monoclonal anti-Recombinant-Hsp90 Co-Chaperone Cdc37 for use in IP and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIP/WB
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDRM2H04
IsotypeIgG
ConjugationUnconjugated
PurificationProtein A/G purified from cell culture supernatant
Dilution RangeIP: 1:20, WB: 1:500-1:1000
Formulation0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide
Storage InstructionSuitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.

Target Information

Gene SymbolCDC37
Gene ID11140
Uniprot IDCDC37_HUMAN

Additional Info

Function Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. Inhibits HSP90AA1 ATPase activity.
Protein Name Hsp90 Co-Chaperone Cdc37
Hsp90 Chaperone Protein Kinase-Targeting Subunit
P50cdc37 Cleaved Into - Hsp90 Co-Chaperone Cdc37 - N-Terminally Processed
Database Links Reactome: R-HSA-1227986
Reactome: R-HSA-1236382
Reactome: R-HSA-5637810
Reactome: R-HSA-5675482
Reactome: R-HSA-8863795
Reactome: R-HSA-9013418
Reactome: R-HSA-9634285
Reactome: R-HSA-9652282
Reactome: R-HSA-9664565
Reactome: R-HSA-9665233
Reactome: R-HSA-9665244
Reactome: R-HSA-9665245
Reactome: R-HSA-9665246
Reactome: R-HSA-9665247
Reactome: R-HSA-9665249
Reactome: R-HSA-9665250
Reactome: R-HSA-9665251
Reactome: R-HSA-9665348
Reactome: R-HSA-9665686
Reactome: R-HSA-9665737
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Hsp90 Co-Chaperone Cdc37 antibody
Anti-Hsp90 Chaperone Protein Kinase-Targeting Subunit antibody
Anti-P50cdc37 Cleaved Into - Hsp90 Co-Chaperone Cdc37 - N-Terminally Processed antibody
Anti-CDC37 antibody
Anti-CDC37A antibody

Information sourced from Uniprot.org

Citations

Product Review