Anti-Recombinant-CD35/CR1/CD21b antibody [8C12] {PerCP} (STJA0030209)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationPerCP
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Recombinant-Complement Component Receptor 1-Like Protein antibody for use in FC in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 8C12 |
| Isotype | IgG |
| Conjugation | PerCP |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Formulation | PBS pH 7.4, 50% glycerol, 0.05% proclin300 |
| Storage Instruction | Store at 4°C for 12 months. Protect from light. Do not freeze. |
Target Information
| Gene Symbol | Cr1l |
| Gene ID | 12946 |
| Uniprot ID | CR1L_MOUSE |
Additional Info
| Function | Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion. |
| Protein Name | Complement Component Receptor 1-Like ProteinComplement Regulatory Protein CrryProtein P65 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Complement Component Receptor 1-Like Protein antibodyAnti-Complement Regulatory Protein Crry antibodyAnti-Protein P65 antibodyAnti-Cr1l antibodyAnti-Crry antibodyAnti-Cry antibody |
Information sourced from Uniprot.org