Anti-Recombinant-CD276/B7-H3 antibody [RM2H83] (STJA0025750)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-CD276/B7-H3 for use in IHC, IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2H83 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4Β°C between 1-2 weeks. For longer term store at-20Β°C for up to 12 months. |
Target Information
| Gene Symbol | Cd276 |
| Gene ID | 102657 |
| Uniprot ID | CD276_MOUSE |
Additional Info
| Function | Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells. |
| Protein Name | Cd276 AntigenB7 Homolog 3B7-H3Costimulatory MoleculeCd Antigen Cd276 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cd276 Antigen antibodyAnti-B7 Homolog 3 antibodyAnti-B7-H3 antibodyAnti-Costimulatory Molecule antibodyAnti-Cd Antigen Cd276 antibodyAnti-Cd276 antibodyAnti-B7h3 antibody |
Information sourced from Uniprot.org