Anti-Recombinant-CCL23/MIP-3/MPIF-1 antibody [RM1Z39] (STJA0024914)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-C-C Motif Chemokine 23 for use in IF and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1Z39 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | CCL23 |
| Gene ID | 6368 |
| Uniprot ID | CCL23_HUMAN |
Additional Info
| Post Translational Modifications | The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms, CCL23(19-99), CCL23(22-99), CCL23(27-99) and CCL23(30-99) exhibit increase in CCR1-mediated signaling and chemotaxis assays in vitro. |
| Function | Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than CCL23. |
| Protein Name | C-C Motif Chemokine 23Ck-Beta-8Ckb-8Macrophage Inflammatory Protein 3Mip-3Myeloid Progenitor Inhibitory Factor 1Mpif-1Small-Inducible Cytokine A23 Cleaved Into - Ccl23(19-99 - Ccl23(22-99 - Ccl23(27-99 - Ccl23(30-99 |
| Database Links | Reactome: R-HSA-416476 P55773-2Reactome: R-HSA-418594 P55773-2Reactome: R-HSA-444473 P55773-2 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 23 antibodyAnti-Ck-Beta-8 antibodyAnti-Ckb-8 antibodyAnti-Macrophage Inflammatory Protein 3 antibodyAnti-Mip-3 antibodyAnti-Myeloid Progenitor Inhibitory Factor 1 antibodyAnti-Mpif-1 antibodyAnti-Small-Inducible Cytokine A23 Cleaved Into - Ccl23(19-99 - Ccl23(22-99 - Ccl23(27-99 - Ccl23(30-99 antibodyAnti-CCL23 antibodyAnti-MIP3 antibodyAnti-MPIF1 antibodyAnti-SCYA23 antibody |
Information sourced from Uniprot.org