Anti-Recombinant-CBS antibody [RM1V05] (STJA0024484)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Cystathionine Beta-Synthase for use in IF, IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1V05 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | CBS |
| Gene ID | 102724560/875 |
| Uniprot ID | CBS_HUMAN |
Additional Info
| Function | Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons. |
| Protein Name | Cystathionine Beta-SynthaseBeta-ThionaseSerine Sulfhydrase |
| Database Links | Reactome: R-HSA-1614603Reactome: R-HSA-2408508 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Cystathionine Beta-Synthase antibodyAnti-Beta-Thionase antibodyAnti-Serine Sulfhydrase antibodyAnti-CBS antibody |
Information sourced from Uniprot.org