Anti-Recombinant-Calretinin antibody (1-178 N-Term) [L122/6] (STJA0040510)
SPECIFICATIONS
ClonalityMonoclonal
HostChicken
ConjugationUnconjugated
IsotypeIgY
ImmunogenFusion protein amino acids 1-178 (N-terminus) of human CALB2 (accession number) produced recombinantly in E. Coli
General Information
| Short Description | Chicken monoclonal anti-Recombinant-Calretinin (1-178 N-Term) for use in ELISA, ICC, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/ICC/IHC/WB |
| Host | Chicken |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | L122/6 |
| Isotype | IgY |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by affinity chromatography |
| Formulation | 1X PBS, 0.05% Sodium Azide pH 7.4 |
| Storage Instruction | Aliquot and store at โค-20ยฐC for long term storage. For short term storage, store at 2-8ยฐC. For maximum recovery of product, centrifuge the vial prior to removing the cap. |
Target Information
| Gene Symbol | CALB2 |
| Gene ID | 794 |
| Uniprot ID | CALB2_HUMAN |
| Immunogen | Fusion protein amino acids 1-178 (N-terminus) of human CALB2 (accession number) produced recombinantly in E. Coli |
| Immunogen Region | 1-178 N-Term |
| Immunogen Sequence | Human |
| Specificity | No cross-reactivity reported |
Additional Info
| Tissue Specificity | Brain. |
| Function | Calcium-binding protein involved in calcium homeostasis and signal transduction. It plays a critical role in buffering intracellular calcium levels and modulating calcium-dependent signaling pathways. Predominantly expressed in specific neuronal populations, influences synaptic plasticity and neuronal excitability, contributing to learning and memory. During embryonic development, it facilitates neuronal differentiation and maturation. |
| Protein Name | CalretininCr29 Kda Calbindin |
| Database Links | |
| Cellular Localisation | SynapseCell ProjectionDendriteLocated In DendriolesSmall Dendrites That Makes Up A Brush Structure Found As The Terminal Specialization Of A Dendrite Of A Unipolar Brush Cell |
| Alternative Antibody Names | Anti-Calretinin antibodyAnti-Cr antibodyAnti-29 Kda Calbindin antibodyAnti-CALB2 antibodyAnti-CAB29 antibody |
Information sourced from Uniprot.org