Anti-Recombinant-BCHE/CHE1 antibody [RM1K50] (STJA0023539)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Cholinesterase for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1K50 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | BCHE |
| Gene ID | 590 |
| Uniprot ID | CHLE_HUMAN |
Additional Info
| Post Translational Modifications | N-glycosylated. No other PTM detected. The major N-glycan structures are of the complex diantennary type with 1 and 2 N-acetylneuraminic acid molecules (Neu5Ac) making up approximately 33% and 47% of the total N-glycans, respectively. Only low amounts of fucosylated diantennary N-glycans are detected (approximately 2%). Triantennary N-glycans with or without fucose amount to approximately 13%, whereas 5% of the total N-glycans are of the oligomannosidic or hybrid type. |
| Function | Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters. |
| Protein Name | CholinesteraseAcylcholine AcylhydrolaseButyrylcholine EsteraseCholine Esterase IiPseudocholinesterase |
| Database Links | Reactome: R-HSA-112311Reactome: R-HSA-1483191Reactome: R-HSA-422085Reactome: R-HSA-9749641 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cholinesterase antibodyAnti-Acylcholine Acylhydrolase antibodyAnti-Butyrylcholine Esterase antibodyAnti-Choline Esterase Ii antibodyAnti-Pseudocholinesterase antibodyAnti-BCHE antibodyAnti-CHE1 antibody |
Information sourced from Uniprot.org