Anti-Recombinant-ATAD2 antibody [RM2H89] (STJA0025756)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Atpase Family Aaa Domain-Containing Protein 2 for use in FC, IF and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IF/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2H89 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | FCM: 1:20-1:100, IF: 1:50-1:200, WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | ATAD2 |
| Gene ID | 29028 |
| Uniprot ID | ATAD2_HUMAN |
Additional Info
| Function | May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. |
| Protein Name | Atpase Family Aaa Domain-Containing Protein 2Aaa Nuclear Coregulator Cancer-Associated ProteinAncca |
| Database Links | Reactome: R-HSA-8866910 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Atpase Family Aaa Domain-Containing Protein 2 antibodyAnti-Aaa Nuclear Coregulator Cancer-Associated Protein antibodyAnti-Ancca antibodyAnti-ATAD2 antibodyAnti-L16 antibodyAnti-PRO2000 antibody |
Information sourced from Uniprot.org