Anti-Recombinant-APOC1 antibody [RM1H96] (STJA0023387)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Apolipoprotein C-I for use in FC, IF, IHC, IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IF/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1H96 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | FCM: 1:20-1:100 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | APOC1 |
| Gene ID | 341 |
| Uniprot ID | APOC1_HUMAN |
Additional Info
| Function | Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein. |
| Protein Name | Apolipoprotein C-IApo-CiApoc-IApolipoprotein C1 Cleaved Into - Truncated Apolipoprotein C-I |
| Database Links | Reactome: R-HSA-8866423Reactome: R-HSA-8964046Reactome: R-HSA-9029569 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Apolipoprotein C-I antibodyAnti-Apo-Ci antibodyAnti-Apoc-I antibodyAnti-Apolipoprotein C1 Cleaved Into - Truncated Apolipoprotein C-I antibodyAnti-APOC1 antibody |
Information sourced from Uniprot.org