Anti-Recombinant-APLP2 antibody [RM2C88] (STJA0025260)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Amyloid Beta Precursor Like Protein 2 for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2C88 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:100-1:200, WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | APLP2 |
| Gene ID | 334 |
| Uniprot ID | APLP2_HUMAN |
Additional Info
| Post Translational Modifications | The BPTI/Kunitz inhibitor domain is O-glycosylated. |
| Function | May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts. |
| Protein Name | Amyloid Beta Precursor Like Protein 2ApphAmyloid BetaA4 Precursor-Like Protein 2Amyloid Protein HomologAmyloid-Like Protein 2Aplp-2Cdei Box-Binding ProteinCdebpSperm Membrane Protein Ywk-Ii |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinNucleus |
| Alternative Antibody Names | Anti-Amyloid Beta Precursor Like Protein 2 antibodyAnti-Apph antibodyAnti-Amyloid Beta antibodyAnti-A4 Precursor-Like Protein 2 antibodyAnti-Amyloid Protein Homolog antibodyAnti-Amyloid-Like Protein 2 antibodyAnti-Aplp-2 antibodyAnti-Cdei Box-Binding Protein antibodyAnti-Cdebp antibodyAnti-Sperm Membrane Protein Ywk-Ii antibodyAnti-APLP2 antibodyAnti-APPL2 antibody |
Information sourced from Uniprot.org