Anti-Recombinant-ACOX1 antibody [RM2F95] (STJA0025564)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-ACOX1 for use in IF, IP and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2F95 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200, IP: 1:20, WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | Acox1 |
| Gene ID | 11430 |
| Uniprot ID | ACOX1_MOUSE |
Additional Info
| Function | Involved in the initial and rate-limiting step of peroxisomal beta-oxidation of straight-chain saturated and unsaturated very-long-chain fatty acids. Catalyzes the desaturation of fatty acyl-CoAs such as palmitoyl-CoA (hexadecanoyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs) such as (2E)-hexadecenoyl-CoA, and donates electrons directly to molecular oxygen (O(2)), thereby producing hydrogen peroxide (H(2)O(2)). Isoform 1: Shows highest activity against medium-chain fatty acyl-CoAs. Shows optimum activity with a chain length of 10 carbons (decanoyl-CoA) in vitro. Isoform 2: Is active against a much broader range of substrates and shows activity towards long-chain acyl-CoAs. |
| Protein Name | Peroxisomal Acyl-Coenzyme A Oxidase 1AoxPalmitoyl-Coa OxidasePeroxisomal Fatty Acyl-Coa OxidaseStraight-Chain Acyl-Coa Oxidase Cleaved Into - Peroxisomal Acyl-Coa Oxidase 1 - A Chain - Peroxisomal Acyl-Coa Oxidase 1 - B Chain - Peroxisomal Acyl-Coa Oxidase 1 - C Chain |
| Database Links | Reactome: R-MMU-2046106Reactome: -MMU-390247Reactome: -MMU-9033241 |
| Cellular Localisation | Peroxisome |
| Alternative Antibody Names | Anti-Peroxisomal Acyl-Coenzyme A Oxidase 1 antibodyAnti-Aox antibodyAnti-Palmitoyl-Coa Oxidase antibodyAnti-Peroxisomal Fatty Acyl-Coa Oxidase antibodyAnti-Straight-Chain Acyl-Coa Oxidase Cleaved Into - Peroxisomal Acyl-Coa Oxidase 1 - A Chain - Peroxisomal Acyl-Coa Oxidase 1 - B Chain - Peroxisomal Acyl-Coa Oxidase 1 - C Chain antibodyAnti-Acox1 antibodyAnti-Acox antibodyAnti-Paox antibody |
Information sourced from Uniprot.org