Anti-Recombinant-Acetyl-Histone H2A-K9 antibody [RM1B99] (STJA0026869)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJA0026869
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General Information

Short DescriptionRabbit monoclonal anti-Recombinant-Acetyl-Histone H2a Type 1-B/E-K9 for use in IF, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIF/IHC/WB
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDRM1B99
IsotypeIgG
ConjugationUnconjugated
PurificationProtein A/G purified from cell culture supernatant
Dilution RangeIF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Formulation0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide
Storage InstructionSuitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.

Target Information

Gene SymbolH2AC4.H2AC8
Gene ID3012/8335
Uniprot IDH2A1B_HUMAN

Additional Info

Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Protein Name Histone H2a Type 1-B/E
Histone H2a.2
Histone H2a/A
Histone H2a/M
Database Links Reactome: R-HSA-110328
Reactome: R-HSA-110329
Reactome: R-HSA-110330
Reactome: R-HSA-110331
Reactome: R-HSA-1221632
Reactome: R-HSA-171306
Reactome: R-HSA-1912408
Reactome: R-HSA-201722
Reactome: R-HSA-212300
Reactome: R-HSA-2299718
Reactome: R-HSA-2559580
Reactome: R-HSA-2559582
Reactome: R-HSA-2559586
Reactome: R-HSA-3214815
Reactome: R-HSA-3214847
Reactome: R-HSA-3214858
Reactome: R-HSA-427359
Reactome: R-HSA-427389
Reactome: R-HSA-427413
Reactome: R-HSA-5250924
Reactome: R-HSA-5334118
Reactome: R-HSA-5578749
Reactome: R-HSA-5617472
Reactome: R-HSA-5625886
Reactome: R-HSA-5689603
Reactome: R-HSA-5689880
Reactome: R-HSA-5689901
Reactome: R-HSA-606279
Reactome: R-HSA-68616
Reactome: R-HSA-73728
Reactome: R-HSA-73772
Reactome: R-HSA-8936459
Reactome: R-HSA-8939236
Reactome: R-HSA-9018519
Reactome: R-HSA-912446
Reactome: R-HSA-9609690
Reactome: R-HSA-9610379
Reactome: R-HSA-9616222
Reactome: R-HSA-9670095
Reactome: R-HSA-9710421
Reactome: R-HSA-977225
Reactome: R-HSA-9821002
Reactome: R-HSA-9841922
Reactome: R-HSA-9843940
Reactome: R-HSA-9843970
Reactome: R-HSA-9845323
Cellular Localisation Nucleus
Chromosome
Alternative Antibody Names Anti-Histone H2a Type 1-B/E antibody
Anti-Histone H2a.2 antibody
Anti-Histone H2a/A antibody
Anti-Histone H2a/M antibody
Anti-H2AC4 antibody
Anti-H2AFM antibody
Anti-HIST1H2AB.H2AC8 antibody
Anti-H2AFA antibody
Anti-HIST1H2AE antibody

Information sourced from Uniprot.org

Citations

Product Review