Anti-Recombinant-ACADVL/VLCAD antibody [RM1X60] (STJA0024737)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Very Long-Chain Specific Acyl-Coa Dehydrogenase-Mitochondrial for use in IHC, IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1X60 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:100-1:200 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | ACADVL |
| Gene ID | 37 |
| Uniprot ID | ACADV_HUMAN |
Additional Info
| Post Translational Modifications | S-nitrosylation at Cys-237 in liver improves catalytic efficiency. |
| Function | Very long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, very long-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 12 to 24 carbons long primary chains. |
| Protein Name | Very Long-Chain Specific Acyl-Coa Dehydrogenase - MitochondrialVlcad |
| Database Links | Reactome: R-HSA-381038Reactome: R-HSA-77305 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinIsoform 2: Mitochondrion Inner Membrane |
| Alternative Antibody Names | Anti-Very Long-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial antibodyAnti-Vlcad antibodyAnti-ACADVL antibodyAnti-VLCAD antibody |
Information sourced from Uniprot.org