| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RBPMS (110-219) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RBPMS |
| Gene ID: |
11030 |
| Uniprot ID: |
RBPMS_HUMAN |
| Immunogen Region: |
110-219 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 110-219 of human RBPMS (NP_001008712.1). |
| Immunogen Sequence: |
LVGTPNPSTPLPNTVPQFIA REPYELTVPALYPSSPEVWA PYPLYPAELAPALPPPAFTY PASLHAQCFSPEAKPNTPVF CPLLQQIRFVSGNVFVTYQP TADQQRELPC |
| Tissue Specificity | Ubiquitously expressed, at various levels depending on the isoform and the tissue. |
| Function | Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA. |
| Protein Name | Rna-Binding Protein With Multiple SplicingRbp-MsHeart And Rrm Expressed SequenceHermes |
| Cellular Localisation | NucleusCytoplasmP-BodyTranslocates Into Cytoplasmic Stress Granules That Probably Correspond To P-Bodies In Response To Oxidative Stress |
| Alternative Antibody Names | Anti-Rna-Binding Protein With Multiple Splicing antibodyAnti-Rbp-Ms antibodyAnti-Heart And Rrm Expressed Sequence antibodyAnti-Hermes antibodyAnti-RBPMS antibodyAnti-HERMES antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
