| Short Description : | Rabbit polyclonal RBM19 (759-960) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RBM19 |
| Gene ID: | 9904 |
| Uniprot ID: | RBM19_HUMAN |
| Immunogen Region: | 759-960 |
| Immunogen Sequence: | CSISKKKNKAGVLLSMGFGF VEYRKPEQAQKALKQLQGHV VDGHKLEVRISERATKPAVT LARKKQVPRKQTTSKILVRN IPFQAHSREIRELFSTFGEL KTVRLPKKMTGTGTHRGFGF VDFLTKQDAKRAFNALCHST HLYGRRLVLEWADSEVTLQA LRRKTAAHFHEPPKKKRSVV LDEILEQLEGSDSDSEEQTL QL |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 759-960 of human RBM19 (NP_057280.2). |
| Tissue Specificity | Expressed in the crypts of Lieberkuhn of the intestine and in intestinal neoplasia (at protein level). |
| Function | Plays a role in embryo pre-implantation development. |
| Protein Name | Probable Rna-Binding Protein 19Rna-Binding Motif Protein 19 |
| Database Links | |
| Cellular Localisation | NucleusNucleolusNucleoplasmCytoplasmChromosomeIn Discrete Foci Distributed Throughout The Cytoplasm And Nucleoplasm During The 4 To 8 Cell Stages And The Morula StageBut Not In The Periphery Of The Nucleolar Precursor Body (Npb)During Blastocyst DevelopmentBecomes Increasingly Localized To The Nucleolus And Less To The CytoplasmAt The Late Blastocyst StageLocalized Predominantly In The NucleolusLocalized In The Nucleolus During Interphase And To The Perichromosomal Sheath During MitosisDoes Not Colocalize In The Cytoplasm With Gw182 In P-BodiesMay Translocate To The Nucleolus Upon Early Embryonic DevelopmentColocalizes With Npm1 During InterphaseBy Late ProphaseMetaphaseAnaphase And TelophaseAssociates With The Chromosome PeripheryBy Telophase Localizes To Npb |
| Alternative Antibody Names | Anti-Probable Rna-Binding Protein 19 antibodyAnti-Rna-Binding Motif Protein 19 antibodyAnti-RBM19 antibodyAnti-KIAA0682 antibody |
Information sourced from Uniprot.org
