Anti-RBFOX3 antibody (1-220) (STJ25310)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NeuN (1-220) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RBFOX3 |
| Gene ID | 146713 |
| Uniprot ID | RFOX3_HUMAN |
| Immunogen Region | 1-220 |
| Immunogen Sequence | MAQPYPPAQYPPPPQNGIPA EYAPPPPHPTQDYSGQTPVP TEHGMTLYTPAQTHPEQPGS EASTQPIAGTQTVPQTDEAA QTDSQPLHPSDPTEKQQPKR LHVSNIPFRFRDPDLRQMFG QFGKILDVEIIFNERGSKGF GFVTFETSSDADRAREKLNG TIVEGRKIEVNNATARVMTN KKTGNPYTNGWKLNPVVGAV YGPEFYAVTGFPYPTTGTAV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of NeuN (NP_001076044.1). |
Additional Info
| Function | Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD). |
| Protein Name | Rna Binding Protein Fox-1 Homolog 3Fox-1 Homolog CNeuronal Nuclei AntigenNeun Antigen |
| Database Links | Reactome: R-HSA-9768919 |
| Cellular Localisation | NucleusCytoplasmLargely Restricted To Neuronal NucleiHoweverSignificant Cytoplasmic Localization In Neurons From Brains From Hiv-Infected Individuals With Cognitive Impairment |
| Alternative Antibody Names | Anti-Rna Binding Protein Fox-1 Homolog 3 antibodyAnti-Fox-1 Homolog C antibodyAnti-Neuronal Nuclei Antigen antibodyAnti-Neun Antigen antibodyAnti-RBFOX3 antibody |
Information sourced from Uniprot.org