• Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using RASSF7 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-RASSF7 antibody (159-208 aa) (STJ95379)

SKU:
STJ95379

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Ras association domain-containing protein 7 (159-208 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RASSF7
Gene ID: 8045
Uniprot ID: RASF7_HUMAN
Immunogen Region: 159-208 aa
Specificity: RASSF7 Polyclonal Antibody detects endogenous levels of RASSF7 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human RASSF7 at the amino acid range 159-208
Function Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.
Protein Name Ras Association Domain-Containing Protein 7
Hras1-Related Cluster Protein 1
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Colocalizes With Gamma-Tubulin
Alternative Antibody Names Anti-Ras Association Domain-Containing Protein 7 antibody
Anti-Hras1-Related Cluster Protein 1 antibody
Anti-RASSF7 antibody
Anti-C11orf13 antibody
Anti-HRC1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance