Anti-RASSF7 antibody (159-208 aa) (STJ95379)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human RASSF7 at the amino acid range 159-208
General Information
| Short Description | Rabbit polyclonal anti-Ras association domain-containing protein 7 (159-208 aa) for use in IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RASSF7 |
| Gene ID | 8045 |
| Uniprot ID | RASF7_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human RASSF7 at the amino acid range 159-208 |
| Immunogen Region | 159-208 aa |
| Specificity | RASSF7 Polyclonal Antibody detects endogenous levels of RASSF7 protein. |
Additional Info
| Function | Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization. |
| Protein Name | Ras Association Domain-Containing Protein 7Hras1-Related Cluster Protein 1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeColocalizes With Gamma-Tubulin |
| Alternative Antibody Names | Anti-Ras Association Domain-Containing Protein 7 antibodyAnti-Hras1-Related Cluster Protein 1 antibodyAnti-RASSF7 antibodyAnti-C11orf13 antibodyAnti-HRC1 antibody |
Information sourced from Uniprot.org