Anti-RARG antibody (168-454) (STJ29584)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RARG (168-454) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RARG |
| Gene ID | 5916 |
| Uniprot ID | RARG_HUMAN |
| Immunogen Region | 168-454 |
| Immunogen Sequence | KKEVKEEGSPDSYELSPQLE ELITKVSKAHQE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 168-199 of human RARG (NP_000957.1). |
Additional Info
| Tissue Specificity | Expressed in aortic endothelial cells (at protein level). |
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function. |
| Protein Name | Retinoic Acid Receptor GammaRar-GammaNuclear Receptor Subfamily 1 Group B Member 3 |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-5362517Reactome: R-HSA-5617472 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Retinoic Acid Receptor Gamma antibodyAnti-Rar-Gamma antibodyAnti-Nuclear Receptor Subfamily 1 Group B Member 3 antibodyAnti-RARG antibodyAnti-NR1B3 antibody |
Information sourced from Uniprot.org