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Anti-RARB antibody (331-380 aa) (STJ95373)

Western blot analysis of lysates from HepG2, Hela cells, (Green) primary antibody was diluted at 1:1000, 4°C over night, secondary antibody was diluted at 1:10000, 37°C 1hour. (Red) loading contrl antibody was diluted at 1:5000 as loading control, 4°C over night, secondary antibody was diluted at 1:10000, 37°C 1hour.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Retinoic Acid Receptor beta Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from HepG2 cells, using Retinoic Acid Receptor beta Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of various cells using RAR Beta Polyclonal Antibody

Anti-RARB antibody (331-380 aa) (STJ95373)

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STJ95373

£46.00 - £226.00

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Retinoic acid receptor beta (331-380 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	RARB
Gene ID:	5915
Uniprot ID:	RARB_HUMAN
Immunogen Region:	331-380 aa
Specificity:	RAR Beta Polyclonal Antibody detects endogenous levels of RAR Beta protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human Retinoic Acid Receptor beta at the amino acid range 331-380

Function	Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
Protein Name	Retinoic Acid Receptor Beta Rar-Beta Hbv-Activated Protein Nuclear Receptor Subfamily 1 Group B Member 2 Rar-Epsilon
Database Links	Reactome: R-HSA-383280 Reactome: R-HSA-5362517 Reactome: R-HSA-5617472
Cellular Localisation	Nucleus Cytoplasm Isoform Beta-1: Nucleus Isoform Beta-2: Nucleus Isoform Beta-4: Cytoplasm
Alternative Antibody Names	Anti-Retinoic Acid Receptor Beta antibody Anti-Rar-Beta antibody Anti-Hbv-Activated Protein antibody Anti-Nuclear Receptor Subfamily 1 Group B Member 2 antibody Anti-Rar-Epsilon antibody Anti-RARB antibody Anti-HAP antibody Anti-NR1B2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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