Anti-RARB antibody (331-380 aa) (STJ95373)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human Retinoic Acid Receptor beta at the amino acid range 331-380
General Information
| Short Description | Rabbit polyclonal anti-Retinoic acid receptor beta (331-380 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RARB |
| Gene ID | 5915 |
| Uniprot ID | RARB_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human Retinoic Acid Receptor beta at the amino acid range 331-380 |
| Immunogen Region | 331-380 aa |
| Specificity | RAR Beta Polyclonal Antibody detects endogenous levels of RAR Beta protein. |
Additional Info
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function. |
| Protein Name | Retinoic Acid Receptor BetaRar-BetaHbv-Activated ProteinNuclear Receptor Subfamily 1 Group B Member 2Rar-Epsilon |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-5362517Reactome: R-HSA-5617472 |
| Cellular Localisation | NucleusCytoplasmIsoform Beta-1: NucleusIsoform Beta-2: NucleusIsoform Beta-4: Cytoplasm |
| Alternative Antibody Names | Anti-Retinoic Acid Receptor Beta antibodyAnti-Rar-Beta antibodyAnti-Hbv-Activated Protein antibodyAnti-Nuclear Receptor Subfamily 1 Group B Member 2 antibodyAnti-Rar-Epsilon antibodyAnti-RARB antibodyAnti-HAP antibodyAnti-NR1B2 antibody |
Information sourced from Uniprot.org