• Western blot analysis of lysates from HepG2, Hela cells, (Green) primary antibody was diluted at 1:1000, 4°C over night, secondary antibody was diluted at 1:10000, 37°C 1hour. (Red) loading contrl antibody was diluted at 1:5000 as loading control, 4°C over night, secondary antibody was diluted at 1:10000, 37°C 1hour.
  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Retinoic Acid Receptor beta Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from HepG2 cells, using Retinoic Acid Receptor beta Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using RAR Beta Polyclonal Antibody

Anti-RARB antibody (331-380 aa) (STJ95373)

SKU:
STJ95373

€60.00 - €315.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Retinoic acid receptor beta (331-380 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RARB
Gene ID: 5915
Uniprot ID: RARB_HUMAN
Immunogen Region: 331-380 aa
Specificity: RAR Beta Polyclonal Antibody detects endogenous levels of RAR Beta protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Retinoic Acid Receptor beta at the amino acid range 331-380
Function Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
Protein Name Retinoic Acid Receptor Beta
Rar-Beta
Hbv-Activated Protein
Nuclear Receptor Subfamily 1 Group B Member 2
Rar-Epsilon
Database Links Reactome: R-HSA-383280
Reactome: R-HSA-5362517
Reactome: R-HSA-5617472
Cellular Localisation Nucleus
Cytoplasm
Isoform Beta-1: Nucleus
Isoform Beta-2: Nucleus
Isoform Beta-4: Cytoplasm
Alternative Antibody Names Anti-Retinoic Acid Receptor Beta antibody
Anti-Rar-Beta antibody
Anti-Hbv-Activated Protein antibody
Anti-Nuclear Receptor Subfamily 1 Group B Member 2 antibody
Anti-Rar-Epsilon antibody
Anti-RARB antibody
Anti-HAP antibody
Anti-NR1B2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance