Anti-RAPSN/Rapsyn antibody (N-Term) (STJ71976)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-RAPSN/Rapsyn (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 38kDa band observed in Human Skeletal Muscle lysates (calculated MW of 39.9kDa according to NP_116034.2). Recommended concentration: 0.3-1µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | RAPSN |
| Gene ID | 5913 |
| Uniprot ID | RAPSN_HUMAN |
| Accession Number | NP_005046.2; NP_116034.2 |
| Immunogen Region | N-Term |
| Immunogen Sequence | YQSNQTEKALQVWTK |
| Specificity | This antibody is expected to recognize both reported isoforms (NP_005046.2; NP_116034.2). |
Additional Info
| Function | Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. |
| Protein Name | 43 Kda Receptor-Associated Protein Of The SynapseRapsyn43 Kda Postsynaptic ProteinAcetylcholine Receptor-Associated 43 Kda ProteinRing Finger Protein 205 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SidePostsynaptic Cell MembraneCytoplasmCytoskeletonCytoplasmic Surface Of Postsynaptic Membranes |
| Alternative Antibody Names | Anti-43 Kda Receptor-Associated Protein Of The Synapse antibodyAnti-Rapsyn antibodyAnti-43 Kda Postsynaptic Protein antibodyAnti-Acetylcholine Receptor-Associated 43 Kda Protein antibodyAnti-Ring Finger Protein 205 antibodyAnti-RAPSN antibodyAnti-RNF205 antibody |
Information sourced from Uniprot.org