| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RAPGEF6 (145-240) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RAPGEF6 |
| Gene ID: |
51735 |
| Uniprot ID: |
RPGF6_HUMAN |
| Immunogen Region: |
145-240 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 145-240 of human RAPGEF6 (NP_001157858). |
| Immunogen Sequence: |
INYKGERQTITDDVEVNSYL SLPADLTKMHLTENPHPQVT HVSSSQSGCSIASDSGSSSL SDIYQATESEVGDVDLTRLP EGPVDSEDDEEEDEEI |
| Tissue Specificity | Isoform 3 has highest expression levels in the brain, heart, liver, lung and placenta and is barely detectable in skeletal muscle, kidney and pancreas. |
| Function | Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP. |
| Protein Name | Rap Guanine Nucleotide Exchange Factor 6Pdz Domain-Containing Guanine Nucleotide Exchange Factor 2Pdz-Gef2Ra-Gef-2 |
| Cellular Localisation | CytoplasmCell MembraneUpon Binding To M-RasIt Translocates To The Plasma Membrane |
| Alternative Antibody Names | Anti-Rap Guanine Nucleotide Exchange Factor 6 antibodyAnti-Pdz Domain-Containing Guanine Nucleotide Exchange Factor 2 antibodyAnti-Pdz-Gef2 antibodyAnti-Ra-Gef-2 antibodyAnti-RAPGEF6 antibodyAnti-PDZGEF2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
