Anti-RAP1GAP antibody (1-100) [S2MR] (STJ11101912)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal RAP1GAP (1-100) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S2MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RAP1GAP |
| Gene ID | 5909 |
| Uniprot ID | RPGP1_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MIEKMQGSRMDEQRCSFPPP LKTEEDYIPYPSVHEVLGRE GPFPLILLPQFGGYWIEGTN HEITSIPETEPLQSPTTKVK LECNPTARIYRKHFLGKEHF |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Rap1GAP (P47736). |
Additional Info
| Tissue Specificity | Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues. |
| Function | GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. |
| Protein Name | Rap1 Gtpase-Activating Protein 1Rap1gapRap1gap1 |
| Database Links | Reactome: R-HSA-392517Reactome: R-HSA-8853659 |
| Cellular Localisation | Golgi Apparatus MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Rap1 Gtpase-Activating Protein 1 antibodyAnti-Rap1gap antibodyAnti-Rap1gap1 antibodyAnti-RAP1GAP antibodyAnti-KIAA0474 antibodyAnti-RAP1GA1 antibody |
Information sourced from Uniprot.org