| Tissue Specificity | Ubiquitous expression with high levels in trabecular bone, thymus, small intestine, lung, brain and kidney. Weakly expressed in spleen and bone marrow. |
| Function | Receptor for TNFSF11/RANKL/TRANCE/OPGL.essential for RANKL-mediated osteoclastogenesis. Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2. Involved in the regulation of interactions between T-cells and dendritic cells. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 11aOsteoclast Differentiation Factor ReceptorOdfrReceptor Activator Of Nf-KbCd Antigen Cd265 |
| Database Links | Reactome: R-MMU-5668541Reactome: -MMU-5676594 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinMembrane Raft |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 11a antibodyAnti-Osteoclast Differentiation Factor Receptor antibodyAnti-Odfr antibodyAnti-Receptor Activator Of Nf-Kb antibodyAnti-Cd Antigen Cd265 antibodyAnti-Tnfrsf11a antibodyAnti-Rank antibody |
Information sourced from Uniprot.org
