Anti-RALGPS1 antibody (1-300) (STJ117028)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal RALGPS1 (1-300) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RALGPS1 |
| Gene ID | 9649 |
| Uniprot ID | RGPS1_HUMAN |
| Immunogen Region | 1-300 |
| Immunogen Sequence | MYKRNGLMASVLVTSATPQG SSSSDSLEGQSCDYASKSYD AVVFDVLKVTPEEFASQITL MDIPVFKAIQPEELASCGWS KKEKHSLAPNVVAFTRRFNQ VSFWVVREILTAQTLKIRAE ILSHFVKIAKKLLELNNLHS LMSVVSALQSAPIFRLTKTW ALLNRKDKTTFEKLDYLMSK EDNYKRTREYIRSLKMVPSI PYLGIYLLDLIYIDSAYPAS GSIMENEQRSNQMNNILRI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RALGPS1 (NP_055451.1). |
Additional Info
| Tissue Specificity | Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus. |
| Function | Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization. Guanine nucleotide exchange factor for. |
| Protein Name | Ras-Specific Guanine Nucleotide-Releasing Factor Ralgps1Ral Gef With Ph Domain And Sh3-Binding Motif 1Ral Guanine Nucleotide Exchange Factor 2Ralgef 2Rala Exchange Factor Ralgps1 |
| Database Links | |
| Cellular Localisation | CytoplasmCell MembraneAssociates With Membranes Through The Ph Domain |
| Alternative Antibody Names | Anti-Ras-Specific Guanine Nucleotide-Releasing Factor Ralgps1 antibodyAnti-Ral Gef With Ph Domain And Sh3-Binding Motif 1 antibodyAnti-Ral Guanine Nucleotide Exchange Factor 2 antibodyAnti-Ralgef 2 antibodyAnti-Rala Exchange Factor Ralgps1 antibodyAnti-RALGPS1 antibodyAnti-KIAA0351 antibodyAnti-RALGEF2 antibody |
Information sourced from Uniprot.org