Anti-RAET1G antibody (192-242 aa) (STJ197610)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human RET1G at the amino acid range 192-242
General Information
| Short Description | Rabbit polyclonal anti-UL-16 binding protein 5 (192-242 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RAET1G |
| Gene ID | 353091 |
| Uniprot ID | ULBP5_HUMAN |
| Immunogen | Synthesized peptide derived from the human RET1G at the amino acid range 192-242 |
| Immunogen Region | 192-242 aa |
| Specificity | This antibody detects endogenous levels of human RET1G |
Additional Info
| Post Translational Modifications | The functional form is cleaved C-terminally of the GPI-anchor and yields a 28 kDa protein. |
| Function | Isoform 1: Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. Isoform 3: Down-regulates the expression of KLRK1 and stimulates natural killer cells to secrete IFNG. Isoform 2: Stimulates natural killer cells to secrete IFNG. |
| Protein Name | Ul-16 Binding Protein 5Retinoic Acid Early Transcript 1g Protein |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Isoform 1: Cell MembraneLipid-AnchorGpi-AnchorEndoplasmic ReticulumMainly Found IntracellularlyIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Ul-16 Binding Protein 5 antibodyAnti-Retinoic Acid Early Transcript 1g Protein antibodyAnti-RAET1G antibodyAnti-ULBP5 antibody |
Information sourced from Uniprot.org