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Anti-RAD51D antibody (131-180 aa) (STJ95333)

Western blot analysis of lysates from Jurkat cells, using RAD51L3 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from Jurkat cells using MLH3 antibody.
Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Anti-RAD51D antibody (131-180 aa) (STJ95333)

SKU:

STJ95333

£46.00 - £226.00

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-DNA repair protein RAD51 homolog 4 (131-180 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	RAD51D
Gene ID:	5892
Uniprot ID:	RA51D_HUMAN
Immunogen Region:	131-180 aa
Specificity:	Rad51D Polyclonal Antibody detects endogenous levels of Rad51D protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human RAD51L3 at the amino acid range 131-180

Function	Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the RAD51 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.
Protein Name	Dna Repair Protein Rad51 Homolog 4 R51h3 Rad51 Homolog D Rad51-Like Protein 3 Trad
Database Links	Reactome: R-HSA-5685942 Reactome: R-HSA-5693554 Reactome: R-HSA-5693568 Reactome: R-HSA-5693579 Reactome: R-HSA-5693616 Reactome: R-HSA-6796648 Reactome: R-HSA-9701192 Reactome: R-HSA-9704331 Reactome: R-HSA-9704646 Reactome: R-HSA-9709603
Cellular Localisation	Nucleus Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Chromosome Telomere
Alternative Antibody Names	Anti-Dna Repair Protein Rad51 Homolog 4 antibody Anti-R51h3 antibody Anti-Rad51 Homolog D antibody Anti-Rad51-Like Protein 3 antibody Anti-Trad antibody Anti-RAD51D antibody Anti-RAD51L3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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