Anti-RAB9B antibody (STJ13101910)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide human Ras-related protein Rab-9B (RAB9B, RAB9L, Rab-9L, RAB9-like protein) conjugated to blue carrier protein has been used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-RAB9B for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. Use at a dilution of 1:300 to 1: 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | RAB9B |
| Gene ID | 51209 |
| Uniprot ID | RAB9B_HUMAN |
| Immunogen | A synthetic peptide human Ras-related protein Rab-9B (RAB9B, RAB9L, Rab-9L, RAB9-like protein) conjugated to blue carrier protein has been used as the antigen. |
| Specificity | Specific for RA9B. |
Additional Info
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB9B is involved in the transport of proteins between the endosomes and the trans Golgi network. May use NDE1/NDEL1 as an effector to interact with the dynein motor complex in order to control retrograde trafficking of RAB9-associated late endosomes to the TGN. |
| Protein Name | Ras-Related Protein Rab-9bRab-9-Like ProteinRab-9l |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-6811440Reactome: R-HSA-8873719Reactome: R-HSA-8876198Reactome: R-HSA-9706019 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideCytoplasmic VesiclePhagosomePhagosome MembraneRecruited To Phagosomes Containing SAureus Or MTuberculosis |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-9b antibodyAnti-Rab-9-Like Protein antibodyAnti-Rab-9l antibodyAnti-RAB9B antibodyAnti-RAB9L antibody |
Information sourced from Uniprot.org