Anti-RAB5C antibody (160-210) (STJ13100303)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 160-210 of mouse RAB5C conjugated to an immunogenic carrier protein has been used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-RAB5C (160-210) for use in IHC and WB in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. Use at a dilution of 1:300 to 1: 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Rab5c |
| Gene ID | 19345 |
| Uniprot ID | RAB5C_MOUSE |
| Immunogen | A synthetic peptide from aa region 160-210 of mouse RAB5C conjugated to an immunogenic carrier protein has been used as the antigen. |
| Immunogen Region | 160-210 |
| Specificity | Specific for RAB5C. |
Additional Info
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. |
| Protein Name | Ras-Related Protein Rab-5c |
| Database Links | Reactome: R-MMU-432722Reactome: -MMU-6798695Reactome: -MMU-8856828Reactome: -MMU-8873719Reactome: -MMU-8876198 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideEarly Endosome MembraneMelanosome |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-5c antibodyAnti-Rab5c antibody |
Information sourced from Uniprot.org