| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAB3D |
| Gene ID: | 9545 |
| Uniprot ID: | RAB3D_HUMAN |
| Immunogen Region: | 1-219 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-219 of human RAB3D (NP_004274.1). |
| Immunogen Sequence: | MASAGDTQAGPRDAADQNFD YMFKLLLIGNSSVGKTSFLF RYADDSFTPAFVSTVGIDFK VKTVYRHDKRIKLQIWDTAG QERYRTITTAYYRGAMGFLL MYDIANQESFAAVQDWATQI KTYSWDNAQVILVGNKCDLE DERVVPAEDGRRLADDLGFE FFEASAKENINVKQVFERLV DVICEKMNESLEPSSSSGSN GKGPAVGDAPAPQPSSCSC |
| Tissue Specificity | Highly expressed in granulocytes of peripheral blood. Constitutively expressed at low levels in all hematopoietic cell lines investigated. |
| Post Translational Modifications | Phosphorylation of Thr-86 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM and CHML. |
| Function | Protein transport. Probably involved in regulated exocytosis. |
| Protein Name | Ras-Related Protein Rab-3d |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8873719 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic Side |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-3d antibodyAnti-RAB3D antibodyAnti-GOV antibodyAnti-RAB16 antibody |
Information sourced from Uniprot.org