Anti-RAB2B antibody (103-152 aa) (STJ95290)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human RAB2B at the amino acid range 103-152
General Information
| Short Description | Rabbit polyclonal anti-Ras-related protein Rab-2B (103-152 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RAB2B |
| Gene ID | 84932 |
| Uniprot ID | RAB2B_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human RAB2B at the amino acid range 103-152 |
| Immunogen Region | 103-152 aa |
| Specificity | Rab 2B Polyclonal Antibody detects endogenous levels of Rab 2B protein. |
Additional Info
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology. Regulates the compacted morphology of the Golgi (Probable). Promotes cytosolic DNA-induced innate immune responses. Regulates IFN responses against DNA viruses by regulating the CGAS-STING signaling axis. Together with RAB2A redundantly required for efficient autophagic flux. |
| Protein Name | Ras-Related Protein Rab-2b |
| Database Links | Reactome: R-HSA-8873719 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideEndoplasmic Reticulum MembraneGolgi Apparatus MembraneCytoplasmic VesicleSecretory VesicleAcrosomeAutophagosome MembraneLocalized In The Golgi Apparatus In The Round Spermatids And In The Acrosome In The Elongating Spermatid |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-2b antibodyAnti-RAB2B antibody |
Information sourced from Uniprot.org