| Host: |
Goat |
| Applications: |
WB |
| Reactivity: |
Human/Rat/Mouse/Monkey/Canine |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-RAB2, member RAS oncogene family (110aa C-Term) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS, 20% Glycerol and 0.05% Sodium Azide. |
| Purification: |
This antibody is epitope-affinity purified from goat antiserum. |
| Concentration: |
2 mg/ml |
| Dilution Range: |
WB 1:250-1:2000 |
| Storage Instruction: |
For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours. |
| Gene Symbol: |
RAB2A |
| Gene ID: |
5862 |
| Uniprot ID: |
RAB2A_HUMAN |
| Immunogen Region: |
110aa C-Term |
| Accession Number: |
ENSG00000104388 |
| Specificity: |
Detects total levels of Rab2 protein in transfected cells with GFP-Rab2a and GFP-Rab2b by Western blot. |
| Immunogen: |
Purified recombinant peptide derived from within residues 110 aa to the C-terminus of mouse Rab2b produced in E. coli. |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology. Required for protein transport from the endoplasmic reticulum to the Golgi complex. Regulates the compacted morphology of the Golgi. |
| Protein Name | Ras-Related Protein Rab-2a |
| Database Links | Reactome: R-HSA-162658Reactome: R-HSA-8873719 |
| Cellular Localisation | Endoplasmic Reticulum-Golgi Intermediate Compartment MembraneLipid-AnchorMelanosomeEndoplasmic Reticulum MembraneGolgi Apparatus MembraneCytoplasmic VesicleSecretory VesicleAcrosomeLocalized In The Golgi Apparatus In The Round Spermatids And In The Acrosome In The Elongating SpermatidIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-2a antibodyAnti-RAB2A antibodyAnti-RAB2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
