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Anti-RAB14 antibody (110aa C-Term) (STJ140071)

Anti-Rab14 antibody at 1:500 dilution; lysates at 50 µg per lane; rabbit polyclonal to goat IgG (HRP) at 1:10000 dilution

Anti-RAB14 antibody (110aa C-Term) (STJ140071)

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STJ140071

£98.50 - £371.50

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Goat
Applications:	WB/IF
Reactivity:	Human/Rat/Mouse/Monkey/Canine
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-RAB14, member RAS oncogene family (110aa C-Term) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS, 20% Glycerol and 0.05% Sodium Azide.
Purification:	This antibody is epitope-affinity purified from goat antiserum.
Concentration:	2 mg/ml
Dilution Range:	WB 1:250-1:2000 IF 1:25-1:200
Storage Instruction:	For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Gene Symbol:	RAB14
Gene ID:	51552
Uniprot ID:	RAB14_HUMAN
Immunogen Region:	110aa C-Term
Accession Number:	ENSG00000119396
Specificity:	Detects Rab14 by Western blot in transfected cells with GFP-Rab14.
Immunogen:	Purified recombinant peptide derived from within residues 110 aa to the C-terminus of mouse Rab14 produced in E. coli.

Function	Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes. Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.
Protein Name	Ras-Related Protein Rab-14
Database Links	Reactome: R-HSA-1445148 Reactome: R-HSA-1660499 Reactome: R-HSA-6798695 Reactome: R-HSA-8873719 Reactome: R-HSA-8876198
Cellular Localisation	Recycling Endosome Early Endosome Membrane Lipid-Anchor Cytoplasmic Side Golgi Apparatus Membrane Golgi Apparatus Trans-Golgi Network Membrane Cytoplasmic Vesicle Phagosome Recruited To Recycling Endosomes By Dennd6a Recruited To Phagosomes Containing S Aureus Or M Tuberculosis
Alternative Antibody Names	Anti-Ras-Related Protein Rab-14 antibody Anti-RAB14 antibody

Information sourced from Uniprot.org

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