| Short Description : | Rabbit polyclonal anti-Ras-related protein Rab-27B for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RAB27B |
| Gene ID: | 5874 |
| Uniprot ID: | RB27B_HUMAN |
| Immunogen: | Synthesized peptide derived from human RAB27B |
| Specificity: | This antibody detects endogenous levels of RAB27B at Human, Mouse, Rat |
| Function | Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1. May be involved in targeting uroplakins to urothelial apical membranes. |
| Protein Name | Ras-Related Protein Rab-27bC25kg |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-8873719Reactome: R-HSA-8876198 |
| Cellular Localisation | MembraneLipid-AnchorLate Endosome |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-27b antibodyAnti-C25kg antibodyAnti-RAB27B antibody |
Information sourced from Uniprot.org
