Anti-RAB27B antibody (C-Term) (STJ13101937)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from c-terminal region of mouse RAB27B conjugated to blue carrier protein has been used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-RAB27B (C-Term) for use in IHC and WB in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. Use at a dilution of 1:300 to 1: 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Rab27b |
| Gene ID | 80718 |
| Uniprot ID | RB27B_MOUSE |
| Immunogen | A synthetic peptide from c-terminal region of mouse RAB27B conjugated to blue carrier protein has been used as the antigen. |
| Immunogen Region | C-Term |
| Specificity | Specific for RAB27B. |
Additional Info
| Function | Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1. May be involved in targeting uroplakins to urothelial apical membranes. |
| Protein Name | Ras-Related Protein Rab-27b |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-8873719Reactome: -MMU-8876198 |
| Cellular Localisation | MembraneLipid-AnchorLate Endosome |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-27b antibodyAnti-Rab27b antibody |
Information sourced from Uniprot.org