Anti-QSOX1 antibody [SAA1497] (STJA0019925)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Sulfhydryl Oxidase 1 antibody for use in ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA |
| Host | Mouse |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1497 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | QSOX1 |
| Gene ID | 5768 |
| Uniprot ID | QSOX1_HUMAN |
Additional Info
| Post Translational Modifications | N-glycosylated. O-glycosylated on Thr and Ser residues. |
| Function | Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration. |
| Protein Name | Sulfhydryl Oxidase 1HqsoxQuiescin Q6 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-6798695Reactome: R-HSA-8957275 |
| Cellular Localisation | Isoform 1: Golgi Apparatus MembraneSingle-Pass Membrane ProteinSecretedA Small Proportion Is SecretedProbably Via A Proteolytic Cleavage That Removes The Membrane AnchorIsoform 2: SecretedFound In The Extracellular Medium Of Quiescent Cells But Is Not Found In Proliferating Cells |
| Alternative Antibody Names | Anti-Sulfhydryl Oxidase 1 antibodyAnti-Hqsox antibodyAnti-Quiescin Q6 antibodyAnti-QSOX1 antibodyAnti-QSCN6 antibodyAnti-UNQ2520 antibodyAnti-PRO6013 antibody |
Information sourced from Uniprot.org