Anti-QSOX1 antibody [R06-7A8] (STJA0035342)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human Quiescin Q6
General Information
| Short Description | Rabbit monoclonal anti-QSOX1 for use in WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-7A8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | QSOX1 |
| Gene ID | 5768 |
| Uniprot ID | QSOX1_HUMAN |
| Immunogen | A synthetic peptide of human Quiescin Q6 |
Additional Info
| Tissue Specificity | Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney. |
| Post Translational Modifications | N-glycosylated. O-glycosylated on Thr and Ser residues. |
| Function | Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration. |
| Protein Name | Sulfhydryl Oxidase 1HqsoxQuiescin Q6 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-6798695Reactome: R-HSA-8957275 |
| Cellular Localisation | Isoform 1: Golgi Apparatus MembraneSingle-Pass Membrane ProteinSecretedA Small Proportion Is SecretedProbably Via A Proteolytic Cleavage That Removes The Membrane AnchorIsoform 2: SecretedFound In The Extracellular Medium Of Quiescent Cells But Is Not Found In Proliferating Cells |
| Alternative Antibody Names | Anti-Sulfhydryl Oxidase 1 antibodyAnti-Hqsox antibodyAnti-Quiescin Q6 antibodyAnti-QSOX1 antibodyAnti-QSCN6 antibodyAnti-UNQ2520 antibodyAnti-PRO6013 antibody |
Information sourced from Uniprot.org