Anti-QSOX1 antibody (500-550) {Biotin} (STJ502742)

SKU:
STJ502742-100

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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-QSOX1 (500-550) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.55-0.75 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:50-1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: QSOX1
Gene ID: 5768
Uniprot ID: QSOX1_HUMAN
Immunogen Region: 500-550
Immunogen: Synthetic peptide taken within amino acid region 500-550 on human QSOX1 protein.
Tissue Specificity Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney.
Post Translational Modifications N-glycosylated. O-glycosylated on Thr and Ser residues.
Function Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration.
Protein Name Sulfhydryl Oxidase 1
Hqsox
Quiescin Q6
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-381426
Reactome: R-HSA-6798695
Reactome: R-HSA-8957275
Cellular Localisation Isoform 1: Golgi Apparatus Membrane
Single-Pass Membrane Protein
Secreted
A Small Proportion Is Secreted
Probably Via A Proteolytic Cleavage That Removes The Membrane Anchor
Isoform 2: Secreted
Found In The Extracellular Medium Of Quiescent Cells But Is Not Found In Proliferating Cells
Alternative Antibody Names Anti-Sulfhydryl Oxidase 1 antibody
Anti-Hqsox antibody
Anti-Quiescin Q6 antibody
Anti-QSOX1 antibody
Anti-QSCN6 antibody
Anti-UNQ2520 antibody
Anti-PRO6013 antibody

Information sourced from Uniprot.org

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