| Host: |
Goat |
| Applications: |
Pep-ELISA/FC/IHC |
| Reactivity: |
Human/Mouse/Rat/Dog/Cow/Pig |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-Pyruvate Carboxylase (Internal) is suitable for use in ELISA, Flow Cytometry and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
IHC-5µg/mlFC-Flow cytometric analysis of HeLa cells. 10ug/mlELISA-antibody detection limit dilution 1:16000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
PC |
| Gene ID: |
5091 |
| Uniprot ID: |
PYC_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_000911.2; NP_001035806.1; NP_071504.2 |
| Specificity: |
All reported variants (NP_000911.2; NP_001035806.1; NP_071504.2) represent identical protein. |
| Immunogen Sequence: |
KFKEVKKAYVEANQ |
| Function | Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate. |
| Protein Name | Pyruvate Carboxylase - MitochondrialPyruvic CarboxylasePcb |
| Database Links | Reactome: R-HSA-196780Reactome: R-HSA-3371599Reactome: R-HSA-70263 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Pyruvate Carboxylase - Mitochondrial antibodyAnti-Pyruvic Carboxylase antibodyAnti-Pcb antibodyAnti-PC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
