• Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-PYDC1 antibody (25-75 aa) (STJ196561)

SKU:
STJ196561

€60.00 - €315.00
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Pyrin domain-containing protein 1 (25-75 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PYDC1
Gene ID: 260434
Uniprot ID: PYDC1_HUMAN
Immunogen Region: 25-75 aa
Specificity: This antibody detects endogenous levels of PYDC1 at Human
Immunogen: Synthesized peptide derived from the human PYDC1 at the amino acid range 25-75
Post Translational Modifications Phosphorylated.
Function Associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.
Protein Name Pyrin Domain-Containing Protein 1
Paad-Only Protein 1
Pyrin-Only Protein 1
Cellular Pop1
Cpop1
Cellular Localisation Cytoplasm
Recruited To Specks Formed By Pycard Within The Cytoplasm
Alternative Antibody Names Anti-Pyrin Domain-Containing Protein 1 antibody
Anti-Paad-Only Protein 1 antibody
Anti-Pyrin-Only Protein 1 antibody
Anti-Cellular Pop1 antibody
Anti-Cpop1 antibody
Anti-PYDC1 antibody
Anti-ASC2 antibody
Anti-ASCI antibody
Anti-POP1 antibody
Anti-PYC1 antibody

Information sourced from Uniprot.org

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